How do the gut-brain axis and the microbiome relate to autism?

The gut-brain axis refers to the complex and bidirectional communication network between the gastrointestinal (GI) system (the “gut”) and the brain.

This system involves multiple pathways, including neural, hormonal, and immune signaling, which allow the gut and brain to influence each other. While the connection between the gut-brain axis and autism is complex, disruptions in gut health and the composition of the microbiome contribute to the development or severity of autism symptoms.

The gut microbiome also plays a pivotal role in regulating immune function and maintaining overall health. In autistic children, “dysbiosis” (an imbalance in gut bacteria) has been widely observed and is closely linked to both gastrointestinal and neurological symptoms.

This is why the Protocol focuses on the microbiome as a big part of our methodology, addressed through supplements and diet.